Overview

  • Product nameDR2313 (PARP Inhibitor XI)
  • Description
    Potent, brain-penetrant and water-soluble PARP inhibitor
  • Alternative names
    • PARP Inhibitor XI
  • Biological descriptionPotent, brain-penetrant, and water-soluble poly(ADP-ribose) polymerase (PARP) inhibitor. IC50 values are 0.20 and 0.24 µM for PARP-1 and PARP-2, respectively. Neuroprotective in vitro and in vivo.
  • Purity> 99%

Properties

    References for DR2313 (PARP Inhibitor XI) (ab120368)

    This product has been referenced in:
    • Nakajima H  et al. A newly synthesized poly(ADP-ribose) polymerase inhibitor, DR2313 [2-methyl-3,5,7,8-tetrahydrothiopyrano[4,3-d]-pyrimidine-4-one]: pharmacological profiles, neuroprotective effects, and therapeutic time window in cerebral ischemia in rats. J Pharmacol Exp Ther 312:472-81 (2005). Read more (PubMed: 15466246) »

    See 0 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab120368.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"