Overview

  • Product name
  • Description
    Rabbit polyclonal to DRG1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 333-363 of Human DRG1 (NP_004138.1).

  • Positive control
    • HeLa cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab112958 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 41 kDa.

Target

  • Function
    May play a role in cell proliferation, differentiation and death.
  • Tissue specificity
    High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes.
  • Sequence similarities
    Belongs to the GTP1/OBG family.
    Contains 1 G (guanine nucleotide-binding) domain.
  • Domain
    Its C-terminal domain interacts with TAL1.
  • Post-translational
    modifications
    Polyubiquitinated; which induces proteolytic degradation and is impaired by interaction with ZC3H15.
    Sumoylated by UBE2I in response to MEKK1-mediated stimuli.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Developmentally regulated GTP binding protein 1 antibody
    • Developmentally-regulated GTP-binding protein 1 antibody
    • DKFZp434N1827 antibody
    • DRG 1 antibody
    • DRG-1 antibody
    • DRG1 antibody
    • DRG1_HUMAN antibody
    • NEDD 3 antibody
    • NEDD-3 antibody
    • NEDD3 antibody
    • Neural precursor cell expressed developmentally down regulated protein 3 antibody
    • Neural precursor cell expressed developmentally down-regulated protein 3 antibody
    see all

Images

  • Anti-DRG1 antibody (ab112958) at 1/100 dilution + HeLa cell lysate at 35 µg

    Predicted band size : 41 kDa

References

ab112958 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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