Overview

  • Product name
  • Description
    Rabbit polyclonal to DRG1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Saccharomyces cerevisiae, Zebrafish
  • Immunogen

    A synthetic peptide within amino acids: LIVLDVLKPL GHKKIIENEL EGFGIRLNSK PPNIGFKKKD KGGINLTATC, corresponding to amino acids 145-194 of Human DRG1

  • Positive control
    • 721_B cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab80869 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 40 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    May play a role in cell proliferation, differentiation and death.
  • Tissue specificity
    High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes.
  • Sequence similarities
    Belongs to the GTP1/OBG family.
    Contains 1 G (guanine nucleotide-binding) domain.
  • Domain
    Its C-terminal domain interacts with TAL1.
  • Post-translational
    modifications
    Polyubiquitinated; which induces proteolytic degradation and is impaired by interaction with ZC3H15.
    Sumoylated by UBE2I in response to MEKK1-mediated stimuli.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Developmentally regulated GTP binding protein 1 antibody
    • Developmentally-regulated GTP-binding protein 1 antibody
    • DKFZp434N1827 antibody
    • DRG 1 antibody
    • DRG-1 antibody
    • DRG1 antibody
    • DRG1_HUMAN antibody
    • NEDD 3 antibody
    • NEDD-3 antibody
    • NEDD3 antibody
    • Neural precursor cell expressed developmentally down regulated protein 3 antibody
    • Neural precursor cell expressed developmentally down-regulated protein 3 antibody
    see all

Images

  • Anti-DRG1 antibody (ab80869) at 1 µg/ml (in 5% skim milk / PBS buffer) + 721_B cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 40 kDa
    Observed band size : 32 kDa (why is the actual band size different from the predicted?)

References

ab80869 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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