Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion through regulation of the acetylation of the cohesin subunit SMC3.
Defective in sister chromatid cohesion 1 homolog antibody
Defective in sister chromatid cohesion protein 1 homolog antibody
Sister chromatid cohesion protein DCC1 antibody
Western blot - DSCC1 antibody (ab106972)
Anti-DSCC1 antibody (ab106972) at 1/100 dilution + CEM cell line lysate at 35 µg
Predicted band size : 45 kDa
Immunocytochemistry/ Immunofluorescence - Anti-DSCC1 antibody (ab106972)Image courtesy of an Abreview submitted by Dr. Kirk McManus, Univ. of Manitoba/Cancer Care MICB, Canada
ab106972 (1/200) staining DSCC1 in HeLa cells (green). Cells were fixed with paraformaldehyde, permeabilised with 0.5% Triton X100 and counterstained with DAPI in order to highlight the nucleus (red). For further experimental details, please refer to Abreview.