Overview

  • Product name
  • Description
    Goat polyclonal to DTX3
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Cow, Human
  • Immunogen

    Synthetic peptide:

    KNKVTVSKPVWD

    by a Cysteine residue linker, corresponding to internal sequence amino acids 16-27 of Mouse DTX3 (NP_848597.1)

  • Positive control
    • NIH3T3 lysate, Mouse Fetal Brain lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab99092 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.2 - 0.5 µg/ml. Detects a band of approximately 90 kDa (predicted molecular weight: 38 kDa). The observed much higher molecular weight corresponds to earlier findings in literature with different antibodies.

Target

  • Function
    Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context (By similarity). Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
  • Sequence similarities
    Belongs to the Deltex family.
    Contains 1 RING-type zinc finger.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Deltex3 antibody
    • Dtx3 antibody
    • DTX3_HUMAN antibody
    • Protein deltex 3 antibody
    • Protein deltex-3 antibody
    • RING finger protein 154 antibody
    • RNF154 antibody
    see all

Images

  • Anti-DTX3 antibody (ab99092) at 0.3 µg/ml (incubated for 1 hour) + NIH3T3 cell lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 38 kDa

References

ab99092 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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