Overview

  • Product name
    Anti-DUSP10 antibody - Carboxyterminal end
    See all DUSP10 primary antibodies
  • Description
    Rabbit polyclonal to DUSP10 - Carboxyterminal end
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    KLH-conjugated synthetic peptide from the C-terminal region of human DUSP10.

  • Positive control
    • Human breast carcinoma tissue; CEM cell line lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab71532 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 53 kDa.
ELISA 1/1000.
IHC-P 1/50 - 1/100.

Target

  • Function
    Involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily.
  • Sequence similarities
    Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
    Contains 1 rhodanese domain.
    Contains 1 tyrosine-protein phosphatase domain.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Dual specificity phosphatase 10 antibody
    • Dual specificity phosphatase MKP 5 antibody
    • Dual specificity phosphatase MKP5 antibody
    • Dual specificity protein phosphatase 10 antibody
    • DUS10_HUMAN antibody
    • DUSP 10 antibody
    • DUSP10 antibody
    • DUSP10 protein antibody
    • MAP kinase phosphatase 5 antibody
    • Mitogen activated protein kinase phosphatase 5 antibody
    • Mitogen-activated protein kinase phosphatase 5 antibody
    • MKP 5 antibody
    • MKP-5 antibody
    • MKP5 antibody
    • Serine/threonine specific protein phosphatase antibody
    see all

Images

  • Anti-DUSP10 antibody - Carboxyterminal end (ab71532) at 1/60 dilution + CEM cell line lysate at 35 µg

    Predicted band size : 53 kDa
    Observed band size : 70 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 17 kDa,25 kDa. We are unsure as to the identity of these extra bands.
  • Analysis of DUSP10 expression on formalin-fixed, paraffin-embedded human breast carcinoma tissue using ab71532 at 1:50 dilution (peroxidase-conjugated secondary antibody, AEC staining.

References

This product has been referenced in:
  • Chang CC  et al. Downregulation of inflammatory microRNAs by Ig-like transcript 3 is essential for the differentiation of human CD8(+) T suppressor cells. J Immunol 188:3042-52 (2012). WB ; Human . Read more (PubMed: 22387553) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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