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Storage instructions Shipped at 4°C. Store at 4°C (stable for up to 12 months). Store at -20°C or -80°C.
Storage buffer Preservative: 0.05% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4
Concentration information loading...
Purity Protein G purified
Purification notes This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Clone number 2295E1a
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent dilution. Predicted molecular weight: 44 kDa.
Use at an assay dependent dilution.
Function Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.
Sequence similarities Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. Contains 1 rhodanese domain. Contains 1 tyrosine-protein phosphatase domain.
Post-translational modifications Phosphorylation in the C-terminus by ERK1/2 inhibits proteasomal degradation and stabilizes the protein.
Cellular localization Nucleus.
Information by UniProt
Dual specificity phosphatase 4 antibody
Dual specificity protein phosphatase 4 antibody
Dual specificity protein phosphatase hVH2 antibody
Anti-DUSP4 antibody [2295E1a] images
References for Anti-DUSP4 antibody [2295E1a] (ab53753)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"