Overview

  • Product name
    Anti-DUSP4 antibody [2295E1a]
    See all DUSP4 primary antibodies
  • Description
    Mouse monoclonal [2295E1a] to DUSP4
  • Tested applications
    Suitable for: WB, Dot blotmore details
  • Species reactivity
    Reacts with: Recombinant fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment: corresponding to an internal sequence from Human DUSP4.

Properties

Applications

Our Abpromise guarantee covers the use of ab53753 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 44 kDa.
Dot blot Use at an assay dependent dilution.

Target

  • Function
    Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.
  • Sequence similarities
    Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
    Contains 1 rhodanese domain.
    Contains 1 tyrosine-protein phosphatase domain.
  • Post-translational
    modifications
    Phosphorylation in the C-terminus by ERK1/2 inhibits proteasomal degradation and stabilizes the protein.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Dual specificity phosphatase 4 antibody
    • Dual specificity protein phosphatase 4 antibody
    • Dual specificity protein phosphatase hVH2 antibody
    • DUS4_HUMAN antibody
    • DUSP 4 antibody
    • Dusp4 antibody
    • HVH 2 antibody
    • HVH2 antibody
    • MAP kinase phosphatase 2 antibody
    • Mitogen activated protein kinase phosphatase 2 antibody
    • Mitogen-activated protein kinase phosphatase 2 antibody
    • MKP 2 antibody
    • MKP-2 antibody
    • MKP2 antibody
    • Serine/threonine specific protein phosphatase antibody
    • TYP antibody
    • Typ1 antibody
    • VH 2 antibody
    • VH1 homologous phosphatase 2 antibody
    • VH2 antibody
    see all

Images

  • Anti-DUSP4 antibody [2295E1a] (ab53753) + recombinant immunising protein
    Developed using the ECL technique

    Predicted band size : 44 kDa

References

ab53753 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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