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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||1/50 - 1/100.
Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Contains 1 rhodanese domain.
Contains 1 tyrosine-protein phosphatase domain.
Phosphorylation in the C-terminus by ERK1/2 inhibits proteasomal degradation and stabilizes the protein.
Information by UniProt
- Dual specificity phosphatase 4 antibody
- Dual specificity protein phosphatase 4 antibody
- Dual specificity protein phosphatase hVH2 antibody
Anti-DUSP4 antibody images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - DUSP4 antibody (ab60229)
Ab60229 (1:50) staining human DUSP4 in human breast carcinoma tissue by immunohistochemistry using formalin fixed, paraffin embedded tissue.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
BC = breast carcinoma
References for Anti-DUSP4 antibody (ab60229)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"