Overview

  • Product nameAnti-Dux4 antibody
    See all Dux4 primary antibodies
  • Description
    Rabbit polyclonal to Dux4
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 253-283 of Human Dux4 (Q9UBX2).

  • Positive control
    • HL-60 cell line lysates.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.09% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPurified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab110555 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 45 kDa.

Target

  • RelevanceDUX4 is a homeodomain protein with a similar protein sequence to Pax3 and Pax7. Defects in DUX4 may be the cause of facioscapulohumeral muscular dystrophy (FSHD). FSHD is characterized by weakness of the muscles of the face, upper-arm and shoulder girdle. Severity is highly variable. Weakness is slowly progressive and about 20% of affected individuals eventually require a wheelchair. Approximately 70-90% of individuals have inherited the disease-causing deletion from a parent, and approximately 10-30% of affected individuals have FSHD as the result of a de novo deletion. Offsprings of an affected individual have a 50% chance of inheriting the deletion.
  • Cellular localizationNuclear
  • Database links
  • Alternative names
    • Double homeobox protein 10 antibody
    • Double homeobox protein 4 antibody
    • Double homeobox protein 4/10 antibody
    • DUX10 antibody
    • DUX4L1 antibody
    see all

Anti-Dux4 antibody images

  • Anti-Dux4 antibody (ab110555) at 1/100 dilution + HL-60 cell line lysate at 35 µg

    Predicted band size : 45 kDa

References for Anti-Dux4 antibody (ab110555)

ab110555 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"