Overview

  • Product name
    Anti-Dynamin 1 + 2 antibody
  • Description
    Rabbit polyclonal to Dynamin 1 + 2
  • Specificity
    Ab144449 detects total levels of endogenous dynamin proteins 1 and 2. The antibody does not recognize the related dynamin like protein DLP.
  • Tested applications
    Suitable for: IP, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (KLH coupled) corresponding to residues surrounding Tyr231 of human dynamin.

Properties

Applications

Our Abpromise guarantee covers the use of ab14449 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP 1/30.
WB 1/1000. Predicted molecular weight: 97.4 (dynamin1) , 98 (dynamin2) kDa.

Target

  • Relevance
    Dynamin is a family of large GTPases that has been implicated in the formation of nascent vesicles of both endocytotic and secretory processes. Dynamin plays an important role in the internalization of cell surface receptors, a process that attenuates the responsiveness of signal transduction. It has been illustrated that dynamin interacts with signaling proteins such as Src, PLCgamma, PKC and G proteins. Dynamin is phosphorylated by PKC and Src, and its phosphorylation may regulate the endocytosis of cell surface receptors.
  • Cellular localization
    Cell Membrane and Cytoplasmic
  • Database links
  • Alternative names
    • CMTDI 1 antibody
    • CMTDI1 antibody
    • CMTDIB antibody
    • DNM 1 antibody
    • DNM 2 antibody
    • DNM1 antibody
    • DNM2 antibody
    • DYN II antibody
    • DYN2 antibody
    • Dynamin antibody
    • DYNII antibody
    see all

References for Anti-Dynamin 1 + 2 antibody (ab14449)

ab14449 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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