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Anti-Dynamin 1 + 2 antibody
Rabbit polyclonal to Dynamin 1 + 2
Ab144449 detects total levels of endogenous dynamin proteins 1 and 2. The antibody does not recognize the related dynamin like protein DLP.
Synthetic peptide (KLH coupled) corresponding to residues surrounding Tyr231 of human dynamin.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Constituents: 50% Glycerol, BSA, 150mM Sodium chloride, 10mM sodium HEPES. pH 7.5
Concentration information loading...
Protein A purified
Purified by protein A and peptide affinity chromatography.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000. Predicted molecular weight: 97.4 (dynamin1) , 98 (dynamin2) kDa.
Dynamin is a family of large GTPases that has been implicated in the formation of nascent vesicles of both endocytotic and secretory processes. Dynamin plays an important role in the internalization of cell surface receptors, a process that attenuates the responsiveness of signal transduction. It has been illustrated that dynamin interacts with signaling proteins such as Src, PLCgamma, PKC and G proteins. Dynamin is phosphorylated by PKC and Src, and its phosphorylation may regulate the endocytosis of cell surface receptors.
Cell Membrane and Cytoplasmic
CMTDI 1 antibody
References for Anti-Dynamin 1 + 2 antibody (ab14449)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"