Overview

  • Product name
    Anti-Dynein antibody
  • Description
    Rabbit polyclonal to Dynein
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthesized peptide derived from the N-terminal of Human Dynein.

  • Positive control
    • Human lung carcinoma tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer
    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 49.1% PBS, 0.88% Sodium chloride, 50% Glycerol
    Note: PBS (without Mg2+ and Ca2+)
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab111177 is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab111177 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
  • Sequence similarities
    Belongs to the dynein light chain family.
  • Cellular localization
    Cytoplasm > cytoskeleton.
  • Information by UniProt
  • Database links
  • Alternative names
    • 8 kDa dynein light chain b antibody
    • C87222 antibody
    • cytoplasmic antibody
    • Dlc2 antibody
    • DLC8b antibody
    • DNCL1B antibody
    • DYL2_HUMAN antibody
    • Dynein light chain 2 antibody
    • Dynein light chain 2, cytoplasmic antibody
    • Dynein light chain LC8 type 2 antibody
    • Dynein light chain LC8-type 2 antibody
    • Dynll2 antibody
    • MGC17810 antibody
    • MGC72334 antibody
    see all

Images

  • ab111177 at 1/50 dilution, staining Dynein in paraffin-embedded Human lung carcinoma tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide.

References

ab111177 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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