Anti-Dynorphin A antibody (Biotin) (ab48237)

Overview

  • Product nameAnti-Dynorphin A antibody (Biotin)
    See all Dynorphin A primary antibodies
  • Description
    Rabbit polyclonal to Dynorphin A (Biotin)
  • ConjugationBiotin
  • SpecificityThis antibody is specific for Dynorphin A.
  • Tested applicationsSuitable for: RIA, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Guinea pig, Cow, Pig
  • Immunogen

    Synthetic peptide corresponding to Human Dynorphin A aa 207-223 conjugated to Keyhole Limpet Haemocyanin (KLH).
    Sequence:

    CYGGFLRRIRPKLKWDNQ

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
    Constituents: 50% Glycerol, PBS, pH 7.5
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab48237 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
RIA Use at an assay dependent dilution.
ELISA Use at an assay dependent dilution.

Target

  • RelevanceDynorphins are a class of peptides produced by many different populations of neurons, which has some opiate like activity. It is thus classed as an endogenous opioid peptide. The dynorphins, which include dynorphin A, dynorphin B, alpha and beta neoendorphin, and big dynorphin, are all the products of a single gene, 'preprodynorphin'. Dynorphin is produced in many different parts of the brain, including the hypothalamus, the hippocampus and the spinal cord, and has many different physiological actions, depending upon its site of production. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. As such, it may help some individuals against addiction. Blocking dynorphin may help alleviate depression.
  • Cellular localizationSecreted
  • Database links
  • Alternative names
    • Beta neoendorphin dynorphin antibody
    • Dyn A17 antibody
    • Dynorphin A antibody
    • PDYN antibody
    • Preprodynorphin antibody
    • Proenkephalin B antibody
    see all

References for Anti-Dynorphin A antibody (Biotin) (ab48237)

ab48237 has not yet been referenced specifically in any publications.

Product Wall



The UniProt accession number is P01213-

http://www.uniprot.org/uniprot/P01213

Based on the amino acid sequence, dynorphin A (1-17 form) would be expected around 2.25 kDa.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"