Overview

  • Product nameAnti-DYRK3 antibody
    See all DYRK3 primary antibodies
  • Description
    Rabbit polyclonal to DYRK3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 71-120 (GDHTQHFLDG GEMKVEQLFQ EFGNRKSNTI QSDGISDSEK CSPTVSQGKS) of Human DYRK3 (NP_003573)

  • Positive control
    • THP1 cell lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab104405 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 66 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionNegative regulator of EPO-dependent erythropoiesis, may place an upper limit on red cell production during stress erythropoiesis. Inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells. May act by regulating CREB/CRE signaling.
  • Tissue specificityIsoform 1 and isoform 2 are highly expressed in testis and in hematopoietic tissue such as fetal liver, and bone marrow. Isoform 2 is the predominant form in testis. Isoform 1 is the predominant form in fetal liver and bone marrow. Isoform 1 and isoform 2 are present at low levels in heart, pancreas, lymph node, and thymus.
  • Sequence similaritiesBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Autophosphorylated on tyrosine residues.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Dual specificity tyrosine (Y) phosphorylation regulated kinase 3 antibody
    • Dual specificity tyrosine phosphorylation-regulated kinase 3 antibody
    • Dual specificity tyrosine-phosphorylation-regulated kinase 3 antibody
    • Dyrk3 antibody
    • DYRK3_HUMAN antibody
    • DYRK5 antibody
    • hYAK3 2 antibody
    • Protein kinase Dyrk3 antibody
    • RED antibody
    • REDK antibody
    • Regulatory erythroid kinase antibody
    see all

Anti-DYRK3 antibody images

  • Anti-DYRK3 antibody (ab104405) at 1 µg/ml + THP1 cell lysate at 10 µg

    Predicted band size : 66 kDa

References for Anti-DYRK3 antibody (ab104405)

ab104405 has not yet been referenced specifically in any publications.

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