Overview

  • Product name
  • Description
    Rabbit polyclonal to DYRK3
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Recombinant protein fragment corresponding to a region within amino acids 243 and 542 of DYRK3.

  • Positive control
    • Raji cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab96617 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 66 kDa.

Target

  • Function
    Negative regulator of EPO-dependent erythropoiesis, may place an upper limit on red cell production during stress erythropoiesis. Inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells. May act by regulating CREB/CRE signaling.
  • Tissue specificity
    Isoform 1 and isoform 2 are highly expressed in testis and in hematopoietic tissue such as fetal liver, and bone marrow. Isoform 2 is the predominant form in testis. Isoform 1 is the predominant form in fetal liver and bone marrow. Isoform 1 and isoform 2 are present at low levels in heart, pancreas, lymph node, and thymus.
  • Sequence similarities
    Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Autophosphorylated on tyrosine residues.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Dual specificity tyrosine (Y) phosphorylation regulated kinase 3 antibody
    • Dual specificity tyrosine phosphorylation-regulated kinase 3 antibody
    • Dual specificity tyrosine-phosphorylation-regulated kinase 3 antibody
    • Dyrk3 antibody
    • DYRK3_HUMAN antibody
    • DYRK5 antibody
    • hYAK3 2 antibody
    • Protein kinase Dyrk3 antibody
    • RED antibody
    • REDK antibody
    • Regulatory erythroid kinase antibody
    see all

Images

  • Anti-DYRK3 antibody (ab96617) at 1/1000 dilution + Raji whole cell lyaste at 30 µg

    Predicted band size : 66 kDa

References

ab96617 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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