Recombinant
RabMAb

Anti-DYRK3 antibody [EPR6078(2)] (ab155949)

Overview

  • Product name
    Anti-DYRK3 antibody [EPR6078(2)]
    See all DYRK3 primary antibodies
  • Description
    Rabbit monoclonal [EPR6078(2)] to DYRK3
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, ICC/IFmore details
    Unsuitable for: Flow Cyt,IHC-P or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to residues within Human DYRK3 (UniProt: O43781).

  • Positive control
    • Jurkat, THP1 and HepG2 cell lysates; HeLa cells.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab155949 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 66 kDa.
ICC/IF 1/100 - 1/250.
  • Application notes
    Is unsuitable for Flow Cyt,IHC-P or IP.
  • Target

    • Function
      Negative regulator of EPO-dependent erythropoiesis, may place an upper limit on red cell production during stress erythropoiesis. Inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells. May act by regulating CREB/CRE signaling.
    • Tissue specificity
      Isoform 1 and isoform 2 are highly expressed in testis and in hematopoietic tissue such as fetal liver, and bone marrow. Isoform 2 is the predominant form in testis. Isoform 1 is the predominant form in fetal liver and bone marrow. Isoform 1 and isoform 2 are present at low levels in heart, pancreas, lymph node, and thymus.
    • Sequence similarities
      Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.
      Contains 1 protein kinase domain.
    • Post-translational
      modifications
      Autophosphorylated on tyrosine residues.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • Dual specificity tyrosine (Y) phosphorylation regulated kinase 3 antibody
      • Dual specificity tyrosine phosphorylation-regulated kinase 3 antibody
      • Dual specificity tyrosine-phosphorylation-regulated kinase 3 antibody
      • Dyrk3 antibody
      • DYRK3_HUMAN antibody
      • DYRK5 antibody
      • hYAK3 2 antibody
      • Protein kinase Dyrk3 antibody
      • RED antibody
      • REDK antibody
      • Regulatory erythroid kinase antibody
      see all

    Images

    • All lanes : Anti-DYRK3 antibody [EPR6078(2)] (ab155949) at 1/1000 dilution

      Lane 1 : Jurkat cell lysate
      Lane 2 : THP1 cell lysate
      Lane 3 : HeLa cell lysate
      Lane 4 : HepG2 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size: 66 kDa

    • Immunofluorescent analysis of HepG2 cells, labeling DYRK3 with ab155949 at 1/100 dilution.

    References

    ab155949 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab155949.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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