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Rabbit monoclonal [EPR6078(2)] to DYRK3
ICC/IF more details Unsuitable for:
Flow Cyt,IHC-P or IP
Synthetic peptide, corresponding to residues within Human DYRK3 (UniProt: O43781).
Jurkat, THP1 and HepG2 cell lysates; HeLa cells.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab ® patents
This product is a recombinant rabbit monoclonal antibody.
Shipped at 4°C. Store at -20ºC.
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Tissue culture supernatant
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000 - 1/10000. Predicted molecular weight: 66 kDa.
1/100 - 1/250.
Is unsuitable for Flow Cyt,IHC-P or IP.
Negative regulator of EPO-dependent erythropoiesis, may place an upper limit on red cell production during stress erythropoiesis. Inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells. May act by regulating CREB/CRE signaling.
Isoform 1 and isoform 2 are highly expressed in testis and in hematopoietic tissue such as fetal liver, and bone marrow. Isoform 2 is the predominant form in testis. Isoform 1 is the predominant form in fetal liver and bone marrow. Isoform 1 and isoform 2 are present at low levels in heart, pancreas, lymph node, and thymus.
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.
Contains 1 protein kinase domain.
Autophosphorylated on tyrosine residues.
Information by UniProt
Dual specificity tyrosine (Y) phosphorylation regulated kinase 3 antibody
Dual specificity tyrosine phosphorylation-regulated kinase 3 antibody
Dual specificity tyrosine-phosphorylation-regulated kinase 3 antibody
Western blot - Anti-DYRK3 antibody [EPR6078(2)] (ab155949)
All lanes : Anti-DYRK3 antibody [EPR6078(2)] (ab155949) at 1/1000 dilution Lane 1 : Jurkat cell lysate Lane 2 : THP1 cell lysate Lane 3 : HeLa cell lysate Lane 4 : HepG2 cell lysate Lysates/proteins at 10 µg per lane. Secondary All lanes : Goat anti-rabbit HRP at 1/2000 dilution Predicted band size: 66 kDa
Immunocytochemistry/ Immunofluorescence - Anti-DYRK3 antibody [EPR6078(2)] (ab155949)
Immunofluorescent analysis of HepG2 cells, labeling DYRK3 with ab155949 at 1/100 dilution.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"