• Product nameAnti-Dystrobrevin alpha antibody
    See all Dystrobrevin alpha primary antibodies
  • Description
    Mouse polyclonal to Dystrobrevin alpha
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length Human Dystrobrevin alpha protein (Isoform 2, NP_116757.2).

  • Positive control
    • Dystrobrevin alpha transfected 293T cell lysate.



Our Abpromise guarantee covers the use of ab72793 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesWB: 1/500 - 1/1000. Predicted molecular weight: Isoform 2, 75 kDa; Isoform 1, 84 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMay be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors.
    • Tissue specificityHighly expressed in brain, skeletal and cardiac muscles, and expressed at lower levels in lung, liver and pancreas. Isoform 2 is not expressed in cardiac muscle. Isoform 7 and isoform 8 are only expressed in muscle.
    • Involvement in diseaseDefects in DTNA are the cause of left ventricular non-compaction type 1 (LVNC1) [MIM:604169]. Left ventricular non-compaction is due to an arrest of myocardial morphogenesis. The disorder is characterized by a hypertrophic left ventricule with deep trabeculations and with poor systolic function, with or without associated left ventricular dilation. In some cases, it is associated with other congenital heart anomalies such as ventricular septal defects, pulmonic stenosis and atrial septal defects. The right ventricle may also be affected.
    • Sequence similaritiesBelongs to the dystrophin family. Dystrobrevin subfamily.
      Contains 1 ZZ-type zinc finger.
    • DomainThe coiled coil domain mediates the interaction with dystrophin and utrophin.
    • Post-translational
      Phosphorylation of DTN-1 on tyrosine kinase substrate domain present in the C-terminus.
    • Cellular localizationCytoplasm. Cell junction > synapse. Cell membrane. In peripheral nerves, co-localizes with MAGEE1 in the Schwann cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Alpha-dystrobrevin antibody
      • D18S892E antibody
      • DRP3 antibody
      • DTN antibody
      • DTN-A antibody
      • DTNA antibody
      • DTNA_HUMAN antibody
      • Dystrobrevin alpha antibody
      • Dystrophin related protein 3 antibody
      • Dystrophin-related protein 3 antibody
      • FLJ96209 antibody
      • LVNC1 antibody
      • OTTHUMP00000163151 antibody
      • OTTHUMP00000163152 antibody
      • OTTHUMP00000163153 antibody
      • OTTHUMP00000163154 antibody
      • OTTHUMP00000163155 antibody
      see all

    Anti-Dystrobrevin alpha antibody images

    • All lanes : Anti-Dystrobrevin alpha antibody (ab72793) at 1/500 dilution

      Lane 1 : Dystrobrevin alpha transfected 293T cell lysate
      Lane 2 : Non transfected 293T cell lysate

      Lysates/proteins at 25 µg per lane.

      Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

      Predicted band size : 75 kDa
      Observed band size : 90 kDa (why is the actual band size different from the predicted?)

    References for Anti-Dystrobrevin alpha antibody (ab72793)

    ab72793 has not yet been referenced specifically in any publications.

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