Overview

  • Product nameDYX1C1 peptide

Description

  • NatureSynthetic

Specifications

Our Abpromise guarantee covers the use of ab81940 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-DYX1C1 antibody (ab75185)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • Dyslexia susceptibility 1 candidate 1
    • Dyslexia susceptibility 1 candidate gene 1 protein
    • DYX1
    • DYX1C1
    • DYXC1
    • DYXC1_HUMAN
    • EKN1
    • FLJ37882
    • MGC70618
    • RD
    see all
  • FunctionInvolved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity.
  • Tissue specificityExpressed in several tissues, including brain, lung, kidney and testis. In brain localizes to a fraction of cortical neurons and white matter glial cells.
  • Involvement in diseaseDefects in DYX1C1 may be a cause of susceptibility to dyslexia type 1 (DYX1) [MIM:127700]. A relatively common, complex cognitive disorder characterized by an impairment of reading performance despite adequate motivational, educational and intellectual opportunities. It is a multifactorial trait, with evidence for familial clustering and heritability. Note=A chromosomal aberration involving DYX1C1 has been found in a family affected by dyslexia. Translocation t(2;15)(q11;q21).
  • Sequence similaritiesContains 1 CS domain.
    Contains 3 TPR repeats.
  • Cellular localizationNucleus. Cytoplasm.
  • Information by UniProt

References for DYX1C1 peptide (ab81940)

ab81940 has not yet been referenced specifically in any publications.

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