Overview

  • Product nameAnti-E2F2 antibody
    See all E2F2 primary antibodies
  • Description
    Rabbit polyclonal to E2F2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide:

    LFDSY

    , corresponding to a region around amino acids 425-429 of Human E2F2 (Q14209 ).

  • Positive control
    • HeLa and K562 extracts

Properties

Applications

Our Abpromise guarantee covers the use of ab123374 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 45 kDa (predicted molecular weight: 48 kDa).

Target

  • FunctionTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F-2 binds specifically to RB1 protein, in a cell-cycle dependent manner.
  • Tissue specificityHighest level of expression is found in placenta, low levels are found in lung. Found as well in many immortalized cell lines derived from tumor samples.
  • Sequence similaritiesBelongs to the E2F/DP family.
  • Post-translational
    modifications
    Phosphorylated by CDK2 and cyclin A-CDK2 in the S-phase.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • dE2F2 antibody
    • E2F transcription factor 2 antibody
    • E2F-2 antibody
    • E2F2 antibody
    • E2F2_HUMAN antibody
    • Transcription factor E2F2 antibody
    see all

Anti-E2F2 antibody images

  • All lanes : Anti-E2F2 antibody (ab123374) at 1/500 dilution

    Lane 1 : HeLa extract
    Lane 2 : K562 extract


    Predicted band size : 48 kDa

References for Anti-E2F2 antibody (ab123374)

ab123374 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab123374.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"