Overview

  • Product name
  • Description
    Rabbit polyclonal to E2F4
  • Specificity
    No cross reactivity with other proteins.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human E2F4 aa 228-243 (internal sequence).
    Sequence:

    LPKPALAQSQEASRPN


    Database link: Q16254

Properties

Applications

Our Abpromise guarantee covers the use of ab191036 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 44 kDa.

Target

  • Function
    Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-4 binds with high affinity to RBL1 and RBL2. In some instances, can also bind RB protein.
  • Tissue specificity
    Found in all tissue examined including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
  • Sequence similarities
    Belongs to the E2F/DP family.
  • Developmental stage
    Present in the growth-arrested state, its abundance does not change significantly as cells move into and through the cell cycle.
  • Post-translational
    modifications
    Differentially phosphorylated in vivo.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • E2F 4 antibody
    • E2F transcription factor 4 antibody
    • E2F transcription factor 4 p107/p130 binding antibody
    • E2F-4 antibody
    • E2F4 antibody
    • E2F4_HUMAN antibody
    • p107/p130 binding protein antibody
    • Transcription factor E2F 4 antibody
    • Transcription factor E2F4 antibody
    see all

Images

  • All lanes : Anti-E2F4 antibody (ab191036) at 0.5 µg/ml

    Lane 1 : Rat Lung Tissue Lysate at 50 µg
    Lane 2 : SMMC Whole Cell Lysate at 40 µg


    Predicted band size : 44 kDa
    Observed band size : 44 kDa

References

ab191036 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab191036.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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