The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent dilution. Detects a band of approximately 38 kDa (predicted molecular weight: 38 kDa).
Use at an assay dependent dilution.
FunctionTranscriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction. It is likely involved in the early responses of resting cells to growth factor stimulation.
Sequence similaritiesBelongs to the E2F/DP family.
Predicted band size : 38 kDa Observed band size : 38 kDa
References for Anti-E2F5 antibody [220D1a] (ab59769)
This product has been referenced in:
Uboldi S et al. A systems biology approach to characterize the regulatory networks leading to trabectedin resistance in an in vitro model of myxoid liposarcoma. PLoS One7:e35423 (2012).
Read more (PubMed: 22523595) »
Jiang Y et al. A potential oncogenic role of the commonly observed E2F5 overexpression in hepatocellular carcinoma. World J Gastroenterol17:470-7 (2011).
Read more (PubMed: 21274376) »