Overview

  • Product nameAnti-E2F8 antibody
    See all E2F8 primary antibodies
  • Description
    Rabbit polyclonal to E2F8
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within internal amino acids 817-866 (QLVAESFFRT PGGPTKPTSS SCMDFEGANK TSLGTLFVPQ RKLEVSTEDV) of Human E2F8 (NP_078956).

  • Positive control
    • COLO205 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab98834 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 94 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionAlong with E2F7, inhibitor of E2F-dependent transcription. Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Directly represses E2F1 transcription. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession.
  • Sequence similaritiesBelongs to the E2F/DP family.
  • DomainBoth DNA-binding domains are required for DNA-binding and are proposed to form an intramolecular structure that is similar to the winged helix structure of the E2F-DP heterodimer.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • E2F 8 antibody
    • E2F family member 82 antibody
    • E2F transcription factor 8 antibody
    • E2F-8 antibody
    • E2f8 antibody
    • E2F8_HUMAN antibody
    • FLJ23311 antibody
    • Transcription factor E2F8 antibody
    see all

Anti-E2F8 antibody images

  • Anti-E2F8 antibody (ab98834) at 1 µg/ml + COLO205 cell lysate at 10 µg

    Predicted band size : 94 kDa

References for Anti-E2F8 antibody (ab98834)

ab98834 has not yet been referenced specifically in any publications.

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