Overview

  • Product nameAnti-E74 like factor 1 antibody
    See all E74 like factor 1 primary antibodies
  • Description
    Rabbit polyclonal to E74 like factor 1
  • Specificityab64937 detects endogenous levels of total E74 like factor 1 protein.
  • Tested applicationsSuitable for: ELISA, ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (Human) from the C terminal region.

  • Positive control
    • A549 cells and cell extracts from 293 and HuvEc cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab64937 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/5000.
ICC/IF 1/500 - 1/1000.
WB 1/500 - 1/1000. Detects a band of approximately 67 kDa (predicted molecular weight: 67 kDa).

Target

  • FunctionTranscription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer.
  • Tissue specificityIn fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis.
  • Sequence similaritiesBelongs to the ETS family.
    Contains 1 ETS DNA-binding domain.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • E74 like factor 1 antibody
    • E74-like factor 1 antibody
    • ELF 1 antibody
    • ELF1 antibody
    • ELF1_HUMAN antibody
    • Ets domain transcription factor antibody
    • ETS related transcription factor Elf 1 antibody
    • ETS related transcription factor Elf1 antibody
    • ets-related transcription factor antibody
    • ETS-related transcription factor Elf-1 antibody
    • mElf 1 antibody
    • p70 antibody
    • Sts1 antibody
    • TRANSCRIPTION FACTOR ELF 1 antibody
    see all

Anti-E74 like factor 1 antibody images

  • This image shows A549 cells stained with ab64937 at 1/500 dilution; with and without the immunising peptide.
  • All lanes : Anti-E74 like factor 1 antibody (ab64937) at 1/500 dilution

    Lane 1 : extracts from 293 cells (5-30µg total protein)
    Lane 2 : extracts from HuvEc cells (5-30µg total protein)
    Lane 3 : extracts from HuvEc cells (5-30µg total protein) and 5-10µg of the immunising peptide.


    Predicted band size : 67 kDa
    Observed band size : 67 kDa

References for Anti-E74 like factor 1 antibody (ab64937)

ab64937 has not yet been referenced specifically in any publications.

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