Overview

  • Product nameAnti-E74 like factor 1 antibody
    See all E74 like factor 1 primary antibodies
  • Description
    Rabbit polyclonal to E74 like factor 1
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rabbit, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Bat, Elephant
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 569-619 of Human E74 like factor 1 (NP_758961.1).

  • Positive control
    • Human Anaplastic Thyroid Carcinoma, Hodgkins Lymphoma, Linitis Plastica Stomach Cancer, Ovarian Carcinoma, Skin Basal Cell Carcinoma

Properties

Applications

Our Abpromise guarantee covers the use of ab99401 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.

Target

  • FunctionTranscription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer.
  • Tissue specificityIn fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis.
  • Sequence similaritiesBelongs to the ETS family.
    Contains 1 ETS DNA-binding domain.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • E74 like factor 1 antibody
    • E74-like factor 1 antibody
    • ELF 1 antibody
    • ELF1 antibody
    • ELF1_HUMAN antibody
    • Ets domain transcription factor antibody
    • ETS related transcription factor Elf 1 antibody
    • ETS related transcription factor Elf1 antibody
    • ets-related transcription factor antibody
    • ETS-related transcription factor Elf-1 antibody
    • mElf 1 antibody
    • p70 antibody
    • Sts1 antibody
    • TRANSCRIPTION FACTOR ELF 1 antibody
    see all

Anti-E74 like factor 1 antibody images

  • Immunohistochemical analysis of formalin-fixed paraffin-embedded human Hodgkin's lymphoma tissue using ab99401 at a dilution of 1/250
  • Immunohistochemical analysis of formalin-fixed paraffin-embedded human ovarian carcinoma tissue using ab99401 at a dilution of 1/250

References for Anti-E74 like factor 1 antibody (ab99401)

ab99401 has not yet been referenced specifically in any publications.

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