Anti-EAAT2 antibody [1H8], prediluted (ab75445)

Overview

  • Product nameAnti-EAAT2 antibody [1H8], prediluted
    See all EAAT2 primary antibodies
  • Description
    Mouse monoclonal [1H8] to EAAT2, prediluted
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant protein corresponding to C-terminal cytoplasmic domain of human EAAT2.

  • EpitopeC-terminal cytoplasmic domain
  • Positive control
    • Human brain tissue

Properties

  • FormPrediluted
  • Storage instructionsShipped at 4°C. Store at +4°C.
  • Concentration information loading...
  • PurityTissue culture supernatant
  • ClonalityMonoclonal
  • Clone number1H8
  • IsotypeIgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab75445 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.

Target

  • FunctionTransports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.
  • Sequence similaritiesBelongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A2 subfamily.
  • Post-translational
    modifications
    Glycosylated.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • EAA2_HUMAN antibody
    • EAAT2 antibody
    • Excitatory amino acid transporter 2 antibody
    • Excitotoxic amino acid transporter 2 antibody
    • Glial high affinity glutamate transporter antibody
    • GLT 1 antibody
    • GLT1 antibody
    • Glutamate aspartate transporter II antibody
    • Glutamate transporter 1 antibody
    • Glutamate/aspartate transporter II antibody
    • Slc1a2 antibody
    • Sodium dependent glutamate aspartate transporter 2 antibody
    • Sodium-dependent glutamate/aspartate transporter 2 antibody
    • solute carrier family 1 (glial high affinity glutamate transporter), member 2 antibody
    • Solute carrier family 1 glial high affinity glutamate transporter member 2 antibody
    • Solute carrier family 1 member 2 antibody
    see all

Anti-EAAT2 antibody [1H8], prediluted images

  • Formalin-fixed, paraffin-embedded human brain stained with ab75445 using peroxidase conjugate and AEC chromogen. Note cytoplasmic and processes staining of glial cells.

References for Anti-EAAT2 antibody [1H8], prediluted (ab75445)

ab75445 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"