Overview

  • Product name
    Anti-EAPP antibody - C-terminal
    See all EAPP primary antibodies
  • Description
    Rabbit polyclonal to EAPP - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human EAPP (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q56P03

  • Positive control
    • WiDr cell line lysate. Human cerebellum tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab171610 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/10 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/100 - 1/500. Predicted molecular weight: 33 kDa.

Target

  • Function
    May play an important role in the fine-tuning of both major E2F1 activities, the regulation of the cell-cycle and the induction of apoptosis. Promotes S-phase entry, and inhibits p14(ARP) expression.
  • Tissue specificity
    Ubiquitously expressed. Highest levels in heart, placenta, skeletal muscle and pancreas. Lower levels in brain, lung and kidney. In the brain, expressed in all regions with high levels in the cerebellum and cerebral cortex. Expressed in COS1 and transformed skin fibroblasts.
  • Developmental stage
    During the cell cycle, expression disappears during mitosis.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1810011O16Rik antibody
    • BM-036 antibody
    • BM036 antibody
    • C14orf11 antibody
    • E2F-associated phosphoprotein antibody
    • EAPP antibody
    • EAPP_HUMAN antibody
    • RGD1309624 antibody
    see all

Images

  • Immunohistochemical analysis of formalin fixed and paraffin embedded Human cerebellum tissue labeling EAPP with ab171610 at 1/10 dilution, followed by peroxidase conjugation of the secondary antibody and DAB staining.

  • Anti-EAPP antibody - C-terminal (ab171610) at 1/100 dilution + WiDr cell line lysate at 35 µg

    Developed using the ECL technique.

    Predicted band size: 33 kDa

References

ab171610 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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