Overview

  • Product nameAnti-EB2 antibody
    See all EB2 primary antibodies
  • Description
    Rabbit polyclonal to EB2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 11-40 of Human EB2 (NP_001137299.1, NP_055083.1, NP_001137298.1).

  • Positive control
    • CEM cell line lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab123579 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 37 kDa.

Target

  • FunctionMay be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.
  • Tissue specificityExpressed in different tumor cell lines. Up-regulated in activated B- and T-lymphocytes.
  • Sequence similaritiesBelongs to the MAPRE family.
    Contains 1 CH (calponin-homology) domain.
    Contains 1 EB1 C-terminal domain.
  • DomainComposed of two functionally independent domains. The N-terminal domain forms an hydrophobic cleft involved in microtubule binding and the C-terminal is involved in the formation of mutually exclusive complexes with APC and DCTN1.
  • Cellular localizationCytoplasm > cytoskeleton. Associated with the microtubule network. Accumulates at the plus end of microtubules.
  • Information by UniProt
  • Database links
  • Alternative names
    • APC binding protein EB1 antibody
    • APC binding protein EB2 antibody
    • APC-binding protein EB2 antibody
    • EB1 antibody
    • EB2 antibody
    • End binding protein 2 antibody
    • End-binding protein 2 antibody
    • H.sapiens mRNA for novel T cell activation protein antibody
    • MAPRE2 antibody
    • MARE2_HUMAN antibody
    • Microtubule associated protein RP/EB family member 2 antibody
    • Microtubule-associated protein RP/EB family member 2 antibody
    • RP1 antibody
    • T cell activation protein EB1 family antibody
    see all

Anti-EB2 antibody images

  • Anti-EB2 antibody (ab123579) at 1/100 dilution + CEM cell line lysate at 35 µg

    Predicted band size : 37 kDa

References for Anti-EB2 antibody (ab123579)

This product has been referenced in:
  • Nakamura S  et al. Dissecting the nanoscale distributions and functions of microtubule-end-binding proteins EB1 and ch-TOG in interphase HeLa cells. PLoS One 7:e51442 (2012). WB ; Human . Read more (PubMed: 23251535) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"