Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab56753 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IHC-P
  • Application notesWB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMay be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.
    • Tissue specificityExpressed in different tumor cell lines. Up-regulated in activated B- and T-lymphocytes.
    • Sequence similaritiesBelongs to the MAPRE family.
      Contains 1 CH (calponin-homology) domain.
      Contains 1 EB1 C-terminal domain.
    • DomainComposed of two functionally independent domains. The N-terminal domain forms an hydrophobic cleft involved in microtubule binding and the C-terminal is involved in the formation of mutually exclusive complexes with APC and DCTN1.
    • Cellular localizationCytoplasm > cytoskeleton. Associated with the microtubule network. Accumulates at the plus end of microtubules.
    • Information by UniProt
    • Database links
    • Alternative names
      • APC binding protein EB1 antibody
      • APC binding protein EB2 antibody
      • APC-binding protein EB2 antibody
      • EB1 antibody
      • EB2 antibody
      • End binding protein 2 antibody
      • End-binding protein 2 antibody
      • H.sapiens mRNA for novel T cell activation protein antibody
      • MAPRE2 antibody
      • MARE2_HUMAN antibody
      • Microtubule associated protein RP/EB family member 2 antibody
      • Microtubule-associated protein RP/EB family member 2 antibody
      • RP1 antibody
      • T cell activation protein EB1 family antibody
      see all

    Anti-EB2 antibody images

    • EB2 antibody (ab56753) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human colon.


    • Predicted band size : 37 kDa
      EB2 antibody (ab56753) at 1ug/lane + K-562 cell lysate at 25ug/lane.

    References for Anti-EB2 antibody (ab56753)

    ab56753 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"