Overview

  • Product nameAnti-EBI3 antibody
    See all EBI3 primary antibodies
  • Description
    Rabbit polyclonal to EBI3
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Recombinant full length Mouse protein.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 0.15M Sodium chloride, 0.02M Potassium phosphate, pH 7.2
  • Concentration information loading...
  • PurityIgG fraction
  • Purification notesThis purified antibody has been heated to 56°C for 30 minutes. The endotoxin content is estimated to be <10 pg/ml by the LAL method.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab92759 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notesELISA: 1/20000 - 1/100000.
    WB: 1/500 - 1/2000. Predicted molecular weight: 25 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionAssociates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.
    • Sequence similaritiesBelongs to the type I cytokine receptor family. Type 3 subfamily.
      Contains 2 fibronectin type-III domains.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • cytokine receptor antibody
      • EBI3 antibody
      • EBV induced gene 3 protein antibody
      • EBV-induced gene 3 protein antibody
      • Epstein Barr virus induced 3 antibody
      • Epstein Barr virus induced gene 3 antibody
      • Epstein Barr virus induced gene 3 protein antibody
      • Epstein-Barr virus-induced gene 3 protein antibody
      • IL 27 subunit beta antibody
      • IL 27B antibody
      • IL-27 subunit beta antibody
      • IL-27B antibody
      • IL27 subunit antibody
      • IL27 subunit beta antibody
      • IL27B antibody
      • IL27B_HUMAN antibody
      • IL35 subunit antibody
      • interleukin 27 subunit beta antibody
      • Interleukin-27 subunit beta antibody
      see all

    Anti-EBI3 antibody images

    • Western blot analysis of 100 ng of HEK 293 cells transfected with mouse EBI3 using 1ug/mL rabbit anti-mouse polyclonal antibody and anti-rabbit secondary on nitrocellulose.

    References for Anti-EBI3 antibody (ab92759)

    ab92759 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab92759.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"