Overview

  • Product name
    Anti-EBNA2 antibody [PE2]
    See all EBNA2 primary antibodies
  • Description
    Mouse monoclonal [PE2] to EBNA2
  • Tested applications
    Suitable for: WB, IP, IHC-Fr, ICC/IFmore details
  • Species reactivity
    Epstein Barr Virus.
  • Immunogen

    Recombinant fusion protein against EBNA2.

Properties

Applications

Our Abpromise guarantee covers the use of ab90543 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 53 kDa.
IP Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.

Target

  • Relevance
    The Epstein-Barr Virus (EBV), also called Human herpesvirus 4 (HHV-4), is a virus of the herpes family and is one of the most common viruses in humans. EBNA2 is one of the few genes of Epstein-Barr virus which are necessary for immortalization of human primary B lymphocytes. The EBNA2 protein acts as a transcriptional activator of several viral and cellular genes.
  • Cellular localization
    Nuclear matrix of host cells
  • Alternative names
    • EBNA2 antibody
    • EBV antibody
    • EBV nuclear antigen 2 antibody
    • Epstein Barr nuclear antigen 2 antibody
    • HHV4 antibody
    • Human Herpesvirus 4 antibody
    see all

References for Anti-EBNA2 antibody [PE2] (ab90543)

This product has been referenced in:
  • Martin KA  et al. Epstein-Barr Virus Oncoprotein LMP1 Mediates Epigenetic Changes in Host Gene Expression through PARP1. J Virol 90:8520-30 (2016). Read more (PubMed: 27440880) »
  • Quan L  et al. PD-1 Blockade Can Restore Functions of T-Cells in Epstein-Barr Virus-Positive Diffuse Large B-Cell Lymphoma In Vitro. PLoS One 10:e0136476 (2015). IHC-P ; Human . Read more (PubMed: 26361042) »

See all 10 Publications for this product

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Application
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Blocking step
2.5% Normal Horse Serum - VectorLabs ImmPRESS™ Excel Amplified HRP Polymer Staining Kit (Anti-Mouse Ig) as blocking agent for 20 minute(s) · Temperature: RT°C
Antigen retrieval step
Heat mediated - Buffer/Enzyme Used: Citrate pH 6.0 Bond Epitope Retrieval Solution 1 (ER1, Leica)
Sample
Rhesus monkey Tissue sections (Esophagus)
Specification
Esophagus
Permeabilization
No
Fixative
10% Neutral Buffered Formalin
Username

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Submitted Mar 16 2015

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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