Overview

  • Product nameAnti-Ebola virus antibody [FE25]
    See all Ebola virus primary antibodies
  • Description
    Mouse monoclonal [FE25] to Ebola virus
  • SpecificityEbola virus, Zaire strain
  • Tested applicationsSuitable for: ICC/IF, ELISAmore details
    Unsuitable for: WB
  • Immunogen

    Formalin inactivated Ebola virus (strain Zaire).

  • General notesConcentration varies from lot to lot and can be provided on request.


    Ebola virus is an enveloped, negative-stranded RNA virus. This virus belongs to the family Filoviridae and has a distinctive morphology similar only to that of Marburg virus, but apparently has no antigenic characteristics of Marburg virus. Its genome is a nonsegmented RNA strand. SDS-PAGE profiles demonstrate the presence of seven structural proteins. These are the major nucleoprotein NP (104 K), glycoprotein GP (125K), L protein (180 K), and four proteins: VP40 (40 K), ‘V’PX (35 K), VP30 (30 K) and VP24 (24 K). All the proteins are encoded by monocistronic mRNA transcripts complementary to virion RNA. GP is the major protein of the surface spikes and only this 125K viral protein is glycosylated.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferpH: 7.20
    Preservative: 0.1% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesPurity tested by electrophoresis.
  • Primary antibody notesEbola virus is an enveloped, negative-stranded RNA virus. This virus belongs to the family Filoviridae and has a distinctive morphology similar only to that of Marburg virus, but apparently has no antigenic characteristics of Marburg virus. Its genome is a nonsegmented RNA strand. SDS-PAGE profiles demonstrate the presence of seven structural proteins. These are the major nucleoprotein NP (104 K), glycoprotein GP (125K), L protein (180 K), and four proteins: VP40 (40 K), ‘V’PX (35 K), VP30 (30 K) and VP24 (24 K). All the proteins are encoded by monocistronic mRNA transcripts complementary to virion RNA. GP is the major protein of the surface spikes and only this 125K viral protein is glycosylated.
  • ClonalityMonoclonal
  • Clone numberFE25
  • IsotypeIgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab1924 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration. PubMed: 25815346
ELISA Use at an assay dependent concentration.
  • Application notesIs unsuitable for WB.
  • References for Anti-Ebola virus antibody [FE25] (ab1924)

    This product has been referenced in:
    • Dowall SD  et al. Effective binding of a phosphatidylserine-targeting antibody to Ebola virus infected cells and purified virions. J Immunol Res 2015:347903 (2015). ICC/IF . Read more (PubMed: 25815346) »

    See 1 Publication for this product

    Product Wall

    Thank you for your enquiry. The immunogen for ab1924, Ebola virus antibody [FE25] was a Formalin inactivated Ebola virus (strain Zaire) preparation. Unfortunately the protein target and epitope have not yet been characterized. I hope this infor...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"