Anti-EBV Early Antigen Diffuse Ea-D antibody [M5042526] (ab30541)

Overview

  • Product name
    Anti-EBV Early Antigen Diffuse Ea-D antibody [M5042526]
  • Description
    Mouse monoclonal [M5042526] to EBV Early Antigen Diffuse Ea-D
  • Specificity
    Ab30541 recognizes Early Diffuse Protein (Ea-D) p52/50 of Epstein Barr Virus. The antibody is reactive in IFA of infected cells, immunoprecipitation of specific viral protein and western blot and it recognizes does recognize strain B98-8 of EBV strain. The clone number has been updated from (8.F.92) to (M5042526) both clone numbers name the same antibody clone.
  • Tested applications
    Suitable for: ELISA, WB, ICC/IF, IPmore details
  • Species reactivity
    Reacts with Epstein-Barr Virus. Not yet tested in other species.
  • Immunogen

    Epstein Barr Virus Early Diffuse Protein (Ea-D) p52/50.

  • General notes

    Abcam is committed to meeting high standards of ethical manufacturing and has decided to discontinue this product by June 2019 as it has been generated by the ascites method. We are sorry for any inconvenience this may cause. 

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.1% Sodium Azide
    Constituents: 40% Glycerol, PBS, pH 7.4
  • Concentration information loading...
  • Purity
    IgG fraction
  • Purification notes
    Ammonium sulfate fractionation and column chromatography.
  • Clonality
    Monoclonal
  • Clone number
    M5042526
  • Isotype
    IgG2
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab30541 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Predicted molecular weight: 43 kDa.
ICC/IF Use at an assay dependent dilution.
IP Use at an assay dependent dilution.

Target

  • Relevance
    The EBV Early Diffuse Antigen Diffuse EA-D or EBV DNA polymerase accessory protein, is an essential component of the viral DNA polymerase and is required for lytic EBV replication. In addition to its polymerase accessory protein function, it has recently been reported that Ea-D is a transcriptional activator, inducing expression of the essential oriLyt promoter, BHLF1.
  • Cellular localization
    Nuclear
  • Alternative names
    • BMRF1 antibody
    • DNA polymerase accessory protein antibody
    • Early antigen protein D antibody
    • EBV Ea D antibody
    • EBV early antigen protein D antibody
    • Epstein Barr virus Ea D antibody
    • Epstein Barr virus early antigen diffuse Ea D antibody
    • Epstein Barr virus early antigen protein D antibody
    • HHV4 Ea D antibody
    • HHV4 early antigen diffuse Ea D antibody
    • HHV4 early antigen protein D antibody
    • Human herpesvirus 4 Ea D antibody
    • Human herpesvirus 4 early antigen diffuse Ea D antibody
    • Human herpesvirus 4 early antigen protein D antibody
    • p48/52 antibody
    • p52/p50 antibody
    see all

References

This product has been referenced in:
  • Tan L  et al. CD95 Signaling Inhibits B Cell Receptor-Mediated Gammaherpesvirus Replication in Apoptosis-Resistant B Lymphoma Cells. J Virol 90:9782-9796 (2016). Read more (PubMed: 27558422) »
  • Traylen C  et al. Identification of Epstein-Barr Virus Replication Proteins in Burkitt's Lymphoma Cells. Pathogens 4:739-51 (2015). WB . Read more (PubMed: 26529022) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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