• Product nameAnti-EBV LMP2A antibody [14B7]
    See all EBV LMP2A primary antibodies
  • Description
    Rat monoclonal [14B7] to EBV LMP2A
  • Specificityab59026 is specific for Epstein-Barr virus LMP2A. Clone 14B7 detects wild-type LMP2A protein.
  • Tested applicationsSuitable for: WB, IP, ICC/IFmore details
    Unsuitable for: IHC-P
  • Species reactivity
    Epstein-Barr virus
  • Immunogen

    Bacterial TrpE-LMP2A fusion protein


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone number14B7
  • MyelomaP3x63-Ag8.653
  • IsotypeIgG2a
  • Research areas


Our Abpromise guarantee covers the use of ab59026 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/1000. Detects a band of approximately 50 kDa.
IP Use at an assay dependent dilution.
ICC/IF Use at an assay dependent dilution.
  • Application notesIs unsuitable for IHC-P.
  • Target

    • RelevanceEpstein Barr virus (EBV) is a member of the herpesvirus family and one of the most common human viruses. Most people become infected with EBV during their lives. Primary infections usually results in infectious mononucleosis (glandular fever) but the virus can also lay dormant in B lymphocytes and when reactivated become associated with more serious disease such as Burkitt's lymphoma, nasopharyngeal carcinoma and Hodgkin's disease. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.
    • Alternative names
      • EBV latent membrane protein 2A antibody
      • Epstein Barr virus antibody
      • HHV4 antibody
      • Human Herpesvirus 4 antibody
      • Latent membrane protein 2 antibody
      • LMP2 antibody
      • Terminal protein antibody
      see all

    References for Anti-EBV LMP2A antibody [14B7] (ab59026)

    This product has been referenced in:
    • Perez EM  et al. Novel Epstein-Barr virus-like particles incorporating gH/gL-EBNA1 or gB-LMP2 induce high neutralizing antibody titers and EBV-specific T-cell responses in immunized mice. Oncotarget 8:19255-19273 (2017). Read more (PubMed: 27926486) »
    • Minamitani T  et al. Evasion of affinity-based selection in germinal centers by Epstein-Barr virus LMP2A. Proc Natl Acad Sci U S A 112:11612-7 (2015). WB ; Mouse . Read more (PubMed: 26305967) »

    See all 7 Publications for this product

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    I am sorry to confirm that because we carry over 90,000 products, it is regrettably not feasible for us to keep small sample sizes of our products.

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    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application Western blot
    Sample Human Cell lysate - whole cell (B cell)
    Loading amount 10 µg
    Specification B cell
    Gel Running Conditions Reduced Denaturing (10%)
    Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 22°C

    Abcam user community

    Verified customer

    Submitted Jun 21 2010

    Thank you for your enquiry. The size of protein detected can vary from 45 kDa to around 66 kDa depending on the level of phosphorylation. Unfortunately we do not have any WB images available but the two papers below using the same clone, will provi...

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