Overview

  • Product nameEC-23
  • Description
    Photostable synthetic retinoid. ATRA analog.
  • Biological descriptionPhotostable synthetic retinoid. All-trans retinoic acid (ATRA) (ab120728) analog. Displays similar biological activity to ATRA. Potently induces stem cell differentiation and enables improved consistency of neuronal differentiation. Induces neurogenesis.
  • Purity> 98%

Properties

  • Chemical name4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl]benzoic acid
  • Molecular weight332.44
  • Chemical structureChemical Structure
  • Molecular formulaC23H24O2
  • CAS Number104561-41-3
  • Storage instructionsStore at +4°C. Store under Desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overviewSoluble in DMSO to 50 mM and in ethanol to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

  • Research areas

    References for EC-23 (ab120807)

    This product has been referenced in:
    • Christie VB  et al. Retinoid supplementation of differentiating human neural progenitors and embryonic stem cells leads to enhanced neurogenesis in vitro. J Neurosci Methods 193:239-45 (2010). Read more (PubMed: 20817032) »
    • Maltman DJ  et al. Proteomic profiling of the stem cell response to retinoic acid and synthetic retinoid analogues: identification of major retinoid-inducible proteins. Mol Biosyst 5:458-71 (2009). Read more (PubMed: 19381361) »
    • Barnard JH  et al. Synthetic retinoids: structure-activity relationships. Chemistry 15:11430-42 (2009). Read more (PubMed: 19821467) »

    See 0 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"