Overview

  • Product nameAnti-ECE2 antibody
    See all ECE2 primary antibodies
  • Description
    Rabbit polyclonal to ECE2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Rat
    Predicted to work with: Mouse, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within internal amino acids 280-329 (YMVELGMLLG GQPTSTRAQM QQVLELEIQL ATITVPQDQR RDEEKIYHKM) of Rat ECE2 (NP_001002815).

  • Positive control
    • Rat Brain Lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab110725 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 86 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionConverts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.
  • Tissue specificityExpressed in brain. Strongly down-regulated in inferior parietal lobe from Alzheimer disease patients (at protein level).
  • Sequence similaritiesIn the N-terminal section; belongs to the methyltransferase superfamily.
    In the C-terminal section; belongs to the peptidase M13 family.
  • Cellular localizationGolgi apparatus membrane. Cytoplasmic granule membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ECE 2 antibody
    • ECE-2 antibody
    • ECE2 antibody
    • ECE2_HUMAN antibody
    • Endothelin converting enzyme 2 antibody
    • Endothelin-converting enzyme 2 region antibody
    • Hypothetical protein MGC2408 antibody
    • KIAA0604 antibody
    • MGC17664 antibody
    • MGC78487 antibody
    see all

Anti-ECE2 antibody images

  • Anti-ECE2 antibody (ab110725) at 1 µg/ml + Rat Brain Lysate at 10 µg

    Predicted band size : 86 kDa

References for Anti-ECE2 antibody (ab110725)

ab110725 has not yet been referenced specifically in any publications.

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