Overview

  • Product name
  • Description
    Rabbit polyclonal to ECT2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 565-594 of Human ECT2 (NP_060568.3).

  • Positive control
    • 293 cell lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab123571 was purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab123571 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 100 kDa.

Target

  • Relevance
    The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.
  • Cellular localization
    ECT2 exhibits nuclear localization in interphase, spreads throughout the cytoplasm in prometaphase, and is condensed in the midbody during cytokinesis
  • Database links
  • Alternative names
    • ECT 2 antibody
    • ECT2 protein antibody
    • Epithelial cell transforming sequence 2 antibody
    • Epithelial cell transforming sequence 2 oncogene antibody
    • Epithelial cell transforming sequence 2 oncogene protein antibody
    • FLJ10461 antibody
    • MGC138291 antibody
    see all

Images

  • Anti-ECT2 antibody (ab123571) at 1/100 dilution + 293 cell lysate at 35 µg

    Predicted band size : 100 kDa

References

This product has been referenced in:
  • Tan H  et al. Oncogenic role of epithelial cell transforming sequence 2 in lung adenocarcinoma cells. Exp Ther Med 12:2088-2094 (2016). WB ; Human . Read more (PubMed: 27698697) »
  • Xie J  et al. Small interfering RNA-induced inhibition of epithelial cell transforming sequence 2 suppresses the proliferation, migration and invasion of osteosarcoma cells. Exp Ther Med 9:1881-1886 (2015). WB ; Human . Read more (PubMed: 26136909) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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