• Product nameAnti-EDC3 antibody
    See all EDC3 primary antibodies
  • Description
    Mouse monoclonal to EDC3
  • Tested applicationsSuitable for: WB, Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-509 of Human EDC3


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • IsotypeIgG1
  • Light chain typekappa
  • Research areas


Our Abpromise guarantee covers the use of ab57780 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml.
Flow Cyt Use 0.1µg for 106 cells. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.


  • FunctionBinds single-stranded RNA. In the process of mRNA degradation, may play a role in mRNA decapping. May play a role in spermiogenesis and oogenesis.
  • Tissue specificityExpressed in theca and granulosa cells in ovary, and in spermatids of the meiotic division part II and apical membrane of Sertoli cells in testis (at protein level). Also expressed in brain and mammary gland.
  • Sequence similaritiesBelongs to the EDC3 family.
    Contains 1 DFDF domain.
    Contains 1 YjeF N-terminal domain.
  • DomainThe DFDF domain is unstructured by itself. It assumes a helical fold upon interaction with DDX6.
  • Cellular localizationCytoplasm > P-body. Processing bodies.
  • Information by UniProt
  • Database links
  • Alternative names
    • EDC 3 antibody
    • edc3 antibody
    • EDC3_HUMAN antibody
    • enhancer of mRNA decapping 3 homolog (S. cerevisiae) antibody
    • Enhancer of mRNA decapping 3 homolog antibody
    • Enhancer of mRNA decapping 3, S. cerevisiae, homolog of antibody
    • Enhancer of mRNA decapping protein 3 antibody
    • Enhancer of mRNA-decapping protein 3 antibody
    • FLJ21128 antibody
    • FLJ31777 antibody
    • hYjeF_N2 antibody
    • hYjeF_N2-15q23 antibody
    • LSM 16 antibody
    • LSM16 antibody
    • LSM16 homolog (EDC3 S. cerevisiae) antibody
    • LSM16 homolog (EDC3, S. cerevisiae) antibody
    • LSM16 homolog antibody
    • YJDC antibody
    • YjeF domain containing antibody
    • YjeF domain containing protein 1 antibody
    • YjeF domain containing protein antibody
    • YjeF domain-containing protein 1 antibody
    • YjeF N-terminal domain-containing protein 2 antibody
    • YjeF_N2 antibody
    • YJEFN2 antibody
    see all

Anti-EDC3 antibody images

  • Overlay histogram showing HeLa cells stained with ab57780 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab57780, 0.1μg/1x106 cells) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H&L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.
  • EDC3 antibody (ab57780) at 1ug/lane + HeLa cell lysate at 25ug/lane.

References for Anti-EDC3 antibody (ab57780)

This product has been referenced in:

See all 4 Publications for this product

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