Anti-EDEM1 antibody - Carboxyterminal end (ab55920)

Overview

  • Product nameAnti-EDEM1 antibody - Carboxyterminal end
    See all EDEM1 primary antibodies
  • Description
    Rabbit polyclonal to EDEM1 - Carboxyterminal end
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to C-terminal residues of human EDEM1.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.01% Sodium Azide
    Constituents: 50% Glycerol, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab55920 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 2 µg/ml. Predicted molecular weight: 74 kDa. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA Use at an assay dependent dilution.

Target

  • RelevanceEDEM1 is directly involved in ER associated degradation (ERAD), and targets misfolded glycoproteins for degradation in an N glycan dependent manner. It lacks mannosidase activity. EDEM1 belongs to the glycosyl hydrolase 47 family.
  • Cellular localizationEndoplasmic reticulum membrane.
  • Database links
  • Alternative names
    • EDEM 1 antibody
    • EDEM antibody
    • Endoplasmic reticulum degradation enhancing alpha mannosidase like protein antibody
    • ER degradation enhancer, mannosidase alpha like 1 antibody
    • ER degradation enhancing alpha mannosidase like 1 antibody
    • ER degradation enhancing alpha-mannosidase like protein 1 antibody
    • KIAA0212 antibody
    see all

Anti-EDEM1 antibody - Carboxyterminal end images

  • Anti-EDEM1 antibody - Carboxyterminal end (ab55920) at 2 µg/ml + Hela Whole Cell Lysate - Staurosporine Treated (48hr, 500nM) at 10 µg

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

    Predicted band size : 74 kDa
    Observed band size : 95 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 50 kDa (possible cross reactivity).

References for Anti-EDEM1 antibody - Carboxyterminal end (ab55920)

ab55920 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab55920.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"