Overview

  • Product name
  • Description
    Rabbit polyclonal to EDEM3
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding a region within C terminal amino acids 854-903 of Human EDEM3 protein according to Q9BZQ6

  • Positive control
    • Human placenta lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Constituents: 2% Sucrose, 98% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab118762 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 105 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes. This process depends on mannose-trimming from the N-glycans. Seems to have alpha 1,2-mannosidase activity.
  • Sequence similarities
    Belongs to the glycosyl hydrolase 47 family.
    Contains 1 PA (protease associated) domain.
  • Domain
    Contains a protease-associated domain (PA) of unknown function.
  • Cellular localization
    Endoplasmic reticulum lumen.
  • Information by UniProt
  • Database links
  • Alternative names
    • alpha-1,2-mannosidase EDEM3 antibody
    • C1orf22 antibody
    • EDEM 3 antibody
    • edem3 antibody
    • EDEM3_HUMAN antibody
    • ER degradation enhancer, mannosidase alpha like 3 antibody
    • ER degradation enhancing alpha mannosidase like 3 antibody
    • ER degradation enhancing alpha mannosidase like protein 3 antibody
    • ER degradation-enhancing alpha-mannosidase-like 3 antibody
    see all

Images

  • Anti-EDEM3 antibody (ab118762) at 1 µg/ml + Human placenta lysates at 10 µg

    Predicted band size : 105 kDa

References

ab118762 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab118762.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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