Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab12250 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at an assay dependent dilution. Detects a band of approximately 50 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionReceptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation.
    • Tissue specificityExpressed in many adult organs, including brain, heart, colon, small intestine, placenta, prostate, ovary, pancreas, testes, spleen, skeletal muscle, and kidney. Little or no expression in liver, lung, thymus, or peripheral blood leukocytes.
    • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
    • Cellular localizationCell surface. Cell membrane. Prior to LPA treatment found predominantly at the cell surface but in the presence of LPA co-localizes with RALA in the endocytic vesicles.
    • Information by UniProt
    • Database links
    • Alternative names
      • 5031439C20 antibody
      • AI326300 antibody
      • EDG 2 antibody
      • Endothelial differentiation gene 2 antibody
      • GPCR 26 antibody
      • Gpcr26 antibody
      • Gpcr91 antibody
      • Kdt2 antibody
      • LPA 1 antibody
      • LPA receptor 1 antibody
      • LPA receptor EDG2 antibody
      • LPA-1 antibody
      • lpA1 antibody
      • Lpar1 antibody
      • LPAR1_HUMAN antibody
      • Lysophosphatidic acid receptor 1 antibody
      • Lysophosphatidic acid receptor Edg-2 antibody
      • Lysophosphatidic acid receptor EDG2 antibody
      • MGC105279 antibody
      • MGC29102 antibody
      • Mrec1.3 antibody
      • rec.1.3 antibody
      • Ventricular zone gene 1 antibody
      • vzg-1 antibody
      • VZG1 antibody
      see all

    References for Anti-EDG2 antibody (ab12250)

    ab12250 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry. All the information we have on species cross reactivity is specified on the datasheet, these are updated as soona s any new information is brought to our attention. As far as we are aware, cross reactivity with mouse ti...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"