Overview

  • Product nameAnti-EDG3 antibody - Aminoterminal end
    See all EDG3 primary antibodies
  • Description
    Rabbit polyclonal to EDG3 - Aminoterminal end
  • SpecificityThis antibody is specific for EDG3 (N term).
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide:

    QPVRGNETLREHYQYVGKLAG

    conjugated to KLH, corresponding to N terminal amino acids 10/30 of Human EDG3

  • Positive control
    • Mouse kidney lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab38324 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 42 kDa (predicted molecular weight: 42 kDa).

Target

  • FunctionReceptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.
  • Tissue specificityExpressed in all tissues, but most abundantly in heart, placenta, kidney, and liver.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • EDG 3 antibody
    • EDG3 antibody
    • Endothelial differentiation G protein coupled receptor 3 antibody
    • Endothelial differentiation G-protein coupled receptor 3 antibody
    • Endothelial differentiation gene 3 antibody
    • Endothelial differentiation sphingolipid G protein coupled receptor 3 antibody
    • FLJ37523 antibody
    • FLJ93220 antibody
    • G protein coupled receptor endothelial differentiation gene 3 antibody
    • LPB 3 antibody
    • LPB3 antibody
    • MGC71696 antibody
    • OTTHUMP00000215691 antibody
    • S1P receptor 3 antibody
    • S1P receptor Edg 3 antibody
    • S1P receptor Edg-3 antibody
    • S1P receptor EDG3 antibody
    • S1P3 antibody
    • S1pr3 antibody
    • S1PR3_HUMAN antibody
    • Sphingosine 1 phosphate receptor 3 antibody
    • Sphingosine 1 phosphate receptor Edg 3 antibody
    • Sphingosine 1 phosphate receptor Edg3 antibody
    • Sphingosine 1-phosphate receptor 3 antibody
    • Sphingosine 1-phosphate receptor Edg-3 antibody
    see all

Anti-EDG3 antibody - Aminoterminal end images

  • Anti-EDG3 antibody - Aminoterminal end (ab38324) at 1/100 dilution + mouse kidney lysate

    Predicted band size : 42 kDa
    Observed band size : 42 kDa
    Additional bands at : 27 kDa. We are unsure as to the identity of these extra bands.

References for Anti-EDG3 antibody - Aminoterminal end (ab38324)

This product has been referenced in:
  • Benamer N  et al. Electrophysiological and functional effects of sphingosine-1-phosphate in mouse ventricular fibroblasts. Biochem Biophys Res Commun 408:6-11 (2011). WB ; Mouse . Read more (PubMed: 21420933) »
  • Illuzzi G  et al. Sphingosine kinase mediates resistance to the synthetic retinoid N-(4-hydroxyphenyl)retinamide in human ovarian cancer cells. J Biol Chem 285:18594-602 (2010). WB ; Human . Read more (PubMed: 20404323) »

See all 3 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"