Overview

  • Product nameAnti-EDG3 antibody [AS61]
    See all EDG3 primary antibodies
  • Description
    Mouse monoclonal [AS61] to EDG3
  • SpecificityThe antibody does not recognize EDG2, 4 or 5.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    Synthetic peptide to C-terminal region of EDG3 (Human).

  • Positive control
    • Human or rat spleen, or rat lung tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab12254 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/10000. Detects a band of approximately 45 kDa (predicted molecular weight: 42.2 kDa).

Target

  • FunctionReceptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.
  • Tissue specificityExpressed in all tissues, but most abundantly in heart, placenta, kidney, and liver.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • EDG 3 antibody
    • EDG3 antibody
    • Endothelial differentiation G protein coupled receptor 3 antibody
    • Endothelial differentiation G-protein coupled receptor 3 antibody
    • Endothelial differentiation gene 3 antibody
    • Endothelial differentiation sphingolipid G protein coupled receptor 3 antibody
    • FLJ37523 antibody
    • FLJ93220 antibody
    • G protein coupled receptor endothelial differentiation gene 3 antibody
    • LPB 3 antibody
    • LPB3 antibody
    • MGC71696 antibody
    • OTTHUMP00000215691 antibody
    • S1P receptor 3 antibody
    • S1P receptor Edg 3 antibody
    • S1P receptor Edg-3 antibody
    • S1P receptor EDG3 antibody
    • S1P3 antibody
    • S1pr3 antibody
    • S1PR3_HUMAN antibody
    • Sphingosine 1 phosphate receptor 3 antibody
    • Sphingosine 1 phosphate receptor Edg 3 antibody
    • Sphingosine 1 phosphate receptor Edg3 antibody
    • Sphingosine 1-phosphate receptor 3 antibody
    • Sphingosine 1-phosphate receptor Edg-3 antibody
    see all

References for Anti-EDG3 antibody [AS61] (ab12254)

ab12254 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"