Overview

  • Product nameAnti-EDG6 antibody
    See all EDG6 primary antibodies
  • Description
    Mouse polyclonal to EDG6
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length, human EDG6 protein (NP_003766.1).

  • Positive control
    • Jurkat cell lysate and EDG6 transfected 293T cell lysate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab89277 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 42 kDa.

Target

  • FunctionReceptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes.
  • Tissue specificitySpecifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. Considerable level of expression in adult and fetal spleen as well as adult peripheral leukocytes and lung. Lower expression in adult thymus, lymph node, bone marrow, and appendix as well as in fetal liver, thymus, and lung.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • EDG6 antibody
    • Endothelial differentiation lysophosphatidic acid G protein coupled receptor 6 antibody
    • Endothelial differentiation G protein coupled receptor 6 antibody
    • Endothelial differentiation G-protein coupled receptor 6 antibody
    • Endothelial differentiation gene 6 antibody
    • LPC1 antibody
    • Lysophospholipid receptor C1 antibody
    • MGC129298 antibody
    • Putative G protein coupled receptor antibody
    • S1P receptor 4 antibody
    • S1P receptor Edg-6 antibody
    • S1P receptor Edg6 antibody
    • S1P4 antibody
    • S1PR4 antibody
    • S1PR4_HUMAN antibody
    • SLP4 antibody
    • Sphingosine 1 phosphate receptor 4 antibody
    • Sphingosine 1 phosphate receptor Edg6 antibody
    • Sphingosine 1-phosphate receptor 4 antibody
    • Sphingosine 1-phosphate receptor Edg-6 antibody
    see all

Anti-EDG6 antibody images

  • Anti-EDG6 antibody (ab89277) at 1 µg/ml + Jurkat cell lysate at 50 µg
    Developed using the ECL technique

    Predicted band size : 42 kDa
    Observed band size : 50 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 24 kDa. We are unsure as to the identity of these extra bands.
  • All lanes : Anti-EDG6 antibody (ab89277) at 1 µg/ml

    Lane 1 : EDG6 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Developed using the ECL technique

    Predicted band size : 42 kDa
    Observed band size : 33 kDa (why is the actual band size different from the predicted?)

References for Anti-EDG6 antibody (ab89277)

ab89277 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"