• Product nameAnti-EDG6 antibody
    See all EDG6 primary antibodies
  • Description
    Rabbit polyclonal to EDG6
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cow, Dog, Pig, Macaque Monkey, Gorilla
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 150 - 250 of Human EDG6.

  • Positive control
    • This antibody gave a positive signal in Jurkat whole cell lysate as well as the following tissue lysates: Human Spleen; Human Tonsil; Human Lymph node.



Our Abpromise guarantee covers the use of ab92993 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 48 kDa (predicted molecular weight: 42 kDa).


  • FunctionReceptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes.
  • Tissue specificitySpecifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. Considerable level of expression in adult and fetal spleen as well as adult peripheral leukocytes and lung. Lower expression in adult thymus, lymph node, bone marrow, and appendix as well as in fetal liver, thymus, and lung.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • EDG6 antibody
    • Endothelial differentiation lysophosphatidic acid G protein coupled receptor 6 antibody
    • Endothelial differentiation G protein coupled receptor 6 antibody
    • Endothelial differentiation G-protein coupled receptor 6 antibody
    • Endothelial differentiation gene 6 antibody
    • LPC1 antibody
    • Lysophospholipid receptor C1 antibody
    • MGC129298 antibody
    • Putative G protein coupled receptor antibody
    • S1P receptor 4 antibody
    • S1P receptor Edg-6 antibody
    • S1P receptor Edg6 antibody
    • S1P4 antibody
    • S1PR4 antibody
    • S1PR4_HUMAN antibody
    • SLP4 antibody
    • Sphingosine 1 phosphate receptor 4 antibody
    • Sphingosine 1 phosphate receptor Edg6 antibody
    • Sphingosine 1-phosphate receptor 4 antibody
    • Sphingosine 1-phosphate receptor Edg-6 antibody
    see all

Anti-EDG6 antibody images

  • All lanes : Anti-EDG6 antibody (ab92993) at 1 µg/ml

    Lane 1 : Human spleen tissue lysate - total protein (ab29699)
    Lane 2 : Tonsil (Human) Tissue Lysate
    Lane 3 : Human lymph node tissue lysate - total protein (ab29871)
    Lane 4 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate

    Lysates/proteins at 10 µg per lane.

    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 42 kDa
    Observed band size : 48 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 56 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 12 minutes

References for Anti-EDG6 antibody (ab92993)

ab92993 has not yet been referenced specifically in any publications.

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