Human Predicted to work with:
Mouse, Xenopus laevis, Zebrafish, Orangutan
Recombinant fragment: IGYVCKCPRG FNGIHCQHNI NECEVEPCKN GGICTDLVAN YSCECPGEFM GRNCQYKCSG PLGIEGGIIS NQQITASSTH RALFGLQKWY PYYARLNKK, corresponding to amino acids 101-199 of Human EDIL3 protein (NP_005702), with a proprietary tag.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 54 kDa.
Use at an assay dependent dilution.
FunctionPromotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development.
Sequence similaritiesContains 3 EGF-like domains. Contains 2 F5/8 type C domains.