Overview

  • Product nameAnti-EFEMP2 antibody
    See all EFEMP2 primary antibodies
  • Description
    Mouse polyclonal to EFEMP2
  • SpecificityThis antibody is reactive against mammalian transfected lysate.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length EFEMP2 protein (Human)

  • Positive control
    • Human kidney tissue lysate and EFEMP2 transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab67665 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: 1/500 - 1/1000. Detects a band of approximately 60 kDa (predicted molecular weight: 49 kDa).
    Detection Antibody Pair.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Involvement in diseaseDefects in EFEMP2 are a cause of cutis laxa autosomal recessive type 1 (ARCL1) [MIM:219100]. Hereditary cutis laxa refers to a heterogeneous group of connective tissue disorders characterized by cutaneous abnormalities and variable systemic manifestations. The most constant clinical feature is loose skin, sagging over the face and trunk. Hereditary cutis laxa is inherited in both autosomal dominant and autosomal recessive modes. ARCL1 shows the most severe phenotype and has the poorest prognosis. In addition to the skin, internal organs enriched in elastic fibers, such as the lung and arteries, are affected.
    • Sequence similaritiesBelongs to the fibulin family.
      Contains 6 EGF-like domains.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • EFEMP 2 antibody
      • EFEMP2 antibody
      • EGF containing fibulin like extracellular matrix protein 2 antibody
      • EGF-containing fibulin-like extracellular matrix protein 2 antibody
      • FBLN 4 antibody
      • FBLN4 antibody
      • FBLN4_HUMAN antibody
      • FIBL 4 antibody
      • FIBL-4 antibody
      • FIBL4 antibody
      • Fibulin 4 antibody
      • Fibulin-4 antibody
      • MBP 1 antibody
      • MBP1 antibody
      • Mutant p53 binding protein 1 antibody
      • Protein UPH1 antibody
      • UPH 1 antibody
      • UPH1 antibody
      • UPH1 protein antibody
      see all

    Anti-EFEMP2 antibody images

    • Anti-EFEMP2 antibody (ab67665) at 1/500 dilution + human kidney tissue lysate at 25 µg

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

      Predicted band size : 49 kDa
      Observed band size : 60 kDa (why is the actual band size different from the predicted?)
    • All lanes : Anti-EFEMP2 antibody (ab67665) at 1/500 dilution

      Lane 1 : EFEMP2 transfected 293T cell lysate
      Lane 2 : Non transfected 293T cell lysate

      Lysates/proteins at 25 µg per lane.

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

      Predicted band size : 49 kDa
      Observed band size : 60 kDa (why is the actual band size different from the predicted?)

    References for Anti-EFEMP2 antibody (ab67665)

    ab67665 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab67665.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"