Overview

  • Product name
  • Description
    Rabbit polyclonal to EFHD2
  • Host species
    Rabbit
  • Specificity
    ab106667 is predicted to not cross-react with EFHD1.
  • Tested applications
    Suitable for: IHC-P, ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A 16 amino acid synthetic peptide near the amino terminus of Human EFHD2 (NP_077305)

  • Positive control
    • Mouse brain tissue lysate and Human brain tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab106667 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml.
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 27 kDa.

Target

  • Function
    May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
  • Tissue specificity
    Found in lymphocytes; preferentially expressed in CD8+ cells.
  • Sequence similarities
    Contains 2 EF-hand domains.
  • Cellular localization
    Membrane raft. In immature B-cell line WEHI231.
  • Information by UniProt
  • Database links
  • Alternative names
    • EF hand domain containing protein 2 antibody
    • EF hand domain family, member D2 antibody
    • EF-hand domain-containing protein D2 antibody
    • EFHD 2 antibody
    • EFHD2 antibody
    • EFHD2_HUMAN antibody
    • RP3-467K16.3 antibody
    • Swiprosin 1 antibody
    • Swiprosin-1 antibody
    • SWS1 antibody
    see all

Images

  • Immunofluorescence of EFHD2 in Human brain tissue with ab106667 at 20 ug/mL.

  • Lane 1 : Anti-EFHD2 antibody (ab106667) at 1 µg/ml
    Lane 2 : Anti-EFHD2 antibody (ab106667) at 2 µg/ml

    All lanes : Mouse brain tissue lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 27 kDa

  • ab106667, at 5 µg/ml, staining EFHD2 in paraffin embedded Human brain tissue by immunohistochemistry.

References

This product has been referenced in:
  • Fan CC  et al. EFHD2 promotes epithelial-to-mesenchymal transition and correlates with postsurgical recurrence of stage I lung adenocarcinoma. Sci Rep 7:14617 (2017). Read more (PubMed: 29097801) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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