Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-AAFKELQSTFK
    • Amino acids
      230 to 240

Associated products

Specifications

Our Abpromise guarantee covers the use of ab45646 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-EFHD2 antibody (ab24368)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • EF hand domain containing protein 2
    • EF hand domain family, member D2
    • EF-hand domain-containing protein D2
    • EFHD 2
    • EFHD2
    • EFHD2_HUMAN
    • RP3-467K16.3
    • Swiprosin 1
    • Swiprosin-1
    • SWS1
    see all
  • Function
    May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
  • Tissue specificity
    Found in lymphocytes; preferentially expressed in CD8+ cells.
  • Sequence similarities
    Contains 2 EF-hand domains.
  • Cellular localization
    Membrane raft. In immature B-cell line WEHI231.
  • Information by UniProt

References

ab45646 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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