The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-EFHD2 antibody (ab24368)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
EF hand domain containing protein 2
EF hand domain family, member D2
EF-hand domain-containing protein D2
FunctionMay regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
Tissue specificityFound in lymphocytes; preferentially expressed in CD8+ cells.
Sequence similaritiesContains 2 EF-hand domains.
Cellular localizationMembrane raft. In immature B-cell line WEHI231.