Overview

  • Product nameAnti-EFTUD2 antibody
    See all EFTUD2 primary antibodies
  • Description
    Rabbit polyclonal to EFTUD2
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide derived from internal region of human EFTUD2.

  • Positive control
    • HUVEC and 293 cells

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab92479 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
IHC-P
  • Application notesELISA: 1/40,000.
    IHC-P: 1/50 - 1/100.
    WB: 1/500 - 1/1000. Predicted molecular weight: 109 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionComponent of the U5 snRNP complex required for pre-mRNA splicing. Binds GTP.
    • Involvement in diseaseDefects in EFTUD2 are the cause of mandibulofacial dysostosis with microcephaly (MFDM) [MIM:610536]. A rare syndrome characterized by progressive microcephaly, midface and malar hypoplasia, micrognathia, microtia, dysplastic ears, preauricular skin tags, significant developmental delay, and speech delay. Many patients have major sequelae, including choanal atresia that results in respiratory difficulties, conductive hearing loss, and cleft palate.
    • Sequence similaritiesBelongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
    • Post-translational
      modifications
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • 116 kDa antibody
      • 116 kDa U5 small nuclear ribonucleoprotein component antibody
      • EFTUD2 antibody
      • Elongation factor Tu GTP binding domain containing 2 antibody
      • Elongation factor Tu GTP-binding domain-containing protein 2 antibody
      • hSNU114 antibody
      • MFDGA antibody
      • MFDM antibody
      • SNRNP116 antibody
      • Snrp116 antibody
      • Snu114 antibody
      • SNU114 homolog antibody
      • U5 116KD antibody
      • U5 small nuclear ribonucleoprotein component antibody
      • U5 snRNP specific protein, 116 kD antibody
      • U5 snRNP specific protein, 116 kDa antibody
      • U5 snRNP-specific protein antibody
      • U5-116 kDa antibody
      • U5-116KD antibody
      • U5S1_HUMAN antibody
      see all

    Anti-EFTUD2 antibody images

    • All lanes : Anti-EFTUD2 antibody (ab92479) at 1/500 dilution

      Lane 1 : HUVEC cells (-peptide)
      Lane 2 : 293 cells (-peptide)
      Lane 3 : HUVEC cells (+peptide)

      Lysates/proteins at 30 µg per lane.


      Predicted band size : 109 kDa
    • Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using ab92479 A) - peptide B) + peptide

    References for Anti-EFTUD2 antibody (ab92479)

    ab92479 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab92479.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"