Overview

  • Product name
  • Description
    Rabbit polyclonal to EGFL7
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to an internal region of Human EGFL7.

  • Positive control
    • Human placenta tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab115786 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Target

  • Function
    Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro.
  • Sequence similarities
    Contains 2 EGF-like domains.
    Contains 1 EMI domain.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • EGF like domain 7 antibody
    • EGF like domain containing protein 7 antibody
    • EGF like domain multiple 7 antibody
    • EGF-like protein 7 antibody
    • EGFL 7 antibody
    • EGFL7 antibody
    • EGFL7_HUMAN antibody
    • Epidermal growth factor like domain protein 7 antibody
    • Epidermal growth factor-like protein 7 antibody
    • MEGF 7 antibody
    • MEGF7 antibody
    • MGC111117 antibody
    • Multiple EGF like domain protein 7 antibody
    • Multiple EGF-like domains protein 7 antibody
    • Multiple epidermal growth factor like domain protein 7 antibody
    • Multiple epidermal growth factor-like domains protein 7 antibody
    • NEU1 antibody
    • NEU1 protein antibody
    • NOTCH4 like protein antibody
    • NOTCH4-like protein antibody
    • RP11 251M1.2 antibody
    • UNQ187/PRO1449 antibody
    • Vascular endothelial statin antibody
    • VE statin antibody
    • VE-statin antibody
    • ZNEU 1 antibody
    • ZNEU1 antibody
    see all

Images

  • Staining of Human EGFL7 in a Formalin/PFA-fixed paraffin-embedded section of Human Placenta using ab115786 at a dilution of 1/100.

References

This product has been referenced in:
  • Hansen TF  et al. Intra-tumoural vessel area estimated by expression of epidermal growth factor-like domain 7 and microRNA-126 in primary tumours and metastases of patients with colorectal cancer: a descriptive study. J Transl Med 13:10 (2015). Human . Read more (PubMed: 25592646) »
  • Hansen TF  et al. Epidermal growth factor-like domain 7 predicts response to first-line chemotherapy and bevacizumab in patients with metastatic colorectal cancer. Mol Cancer Ther 13:2238-45 (2014). Read more (PubMed: 25140000) »

See all 3 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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