This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

Overview

  • Product name
  • Description
    Rabbit polyclonal to Egr1

    This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »

  • Species reactivity

    Predicted to work with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide:

    GEQPYEHLTAESFPDI-C

    conjugated to KLH, corresponding to amino acids 93-108 of Human Egr1.

  • General notes
    Expiration date is 1 year from date of opening.

Properties

Applications

  • Application notes
    Tested in peptide ELISA.
    We have detected a band of 58kDa in mouse embryonic fibroblast whole cell lysate, but we have failed to detect a band at 83kDa (expected size from data from other antibodies). We would appreciate any customer feedback for this antibody.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.
    • Sequence similarities
      Belongs to the EGR C2H2-type zinc-finger protein family.
      Contains 3 C2H2-type zinc fingers.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • AT225 antibody
      • Early growth response 1 antibody
      • Early growth response protein 1 antibody
      • EGR 1 antibody
      • EGR-1 antibody
      • EGR1 antibody
      • EGR1_HUMAN antibody
      • G0S30 antibody
      • KROX 24 antibody
      • KROX24 antibody
      • Nerve growth factor-induced clone A antibody
      • Nerve growth factor-induced protein A antibody
      • NGFI-A antibody
      • NGFIA antibody
      • TIS8 antibody
      • Transcription factor ETR103 antibody
      • Transcription factor Zif268 antibody
      • ZIF 268 antibody
      • ZIF268 antibody
      • Zinc finger protein 225 antibody
      • Zinc finger protein Krox-24 antibody
      • ZNF225 antibody
      see all

    Images

    This Fast-Track antibody is not yet fully characterised. These images represent inconclusive preliminary data.

    • Anti-Egr1 antibody (ab6054) at 1/1500 dilution + Mouse embryonic fibroblast whole cell lysate at 35 µg

      Secondary
      Goat-anti-Rabbit IgG [H&L] at 1/10000 dilution

      Observed band size : 58 kDa (why is the actual band size different from the predicted?)
    • ab6054 at 10 µg/ml staining human ovarian cancinoma.

    References

    This product has been referenced in:

    See 1 Publication for this product

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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